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Application of calcium carbonate

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Time of issue:2020-04-25
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(Summary description)Calcium carbonate is widely used and has applications in many fields of industrial production. This article only introduces its application in food and medicine. Due to the simple structure of calcium carbonate, stable chemical properties (good safety), high calcium content (40% calcium content is the highest calcium content among all edible calcium compounds. Other calcium compounds, such as calcium citrate, calcium lactate , calcium hydrogen phosphate, etc., due to the large molecular weight, the relative calcium content is low).

Application of calcium carbonate

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Application of calcium carbonate

Categories:Industry News
Author:
Origin:
Time of issue:2020-04-25
Views:16

Information

Application of calcium carbonate products

Calcium carbonate is widely used and has applications in many fields of industrial production. This article only introduces its application in food and medicine. Due to the simple structure of calcium carbonate, stable chemical properties (good safety), high calcium content (40% calcium content is the highest calcium content among all edible calcium compounds. Other calcium compounds, such as calcium citrate, calcium lactate , calcium hydrogen phosphate, etc., due to the large molecular weight, the relative calcium content is low).

1. Application of calcium carbonate in the pharmaceutical industry:

1.1 Calcium supplementation: As an active pharmaceutical ingredient (API, active Pharmaceutical Ingredient), calcium carbonate plays a leading role in downstream calcium supplementation preparations. Common calcium supplement preparations are: calcium carbonate tablets, calcium carbonate D3 tablets (swallow or chewable tablets), calcium carbonate D3 granules, calcium carbonate D3 effervescent tablets, calcium carbonate D3 suspensions, etc. Calcium carbonate is used as a calcium supplement API with the largest dosage.

Note: All downstream preparation products can be inquired on the website of the State Drug Administration. The specific method of collection: open the website of the State Drug Administration, click the domestic drug in the drug column, and enter the keyword calcium carbonate in the product column.

1.2 Antiacid: The role of calcium carbonate in the Chinese Pharmacopoeia is not only calcium supplementation, but also antacid. Calcium carbonate can be used as the main component of anti-gastric acid preparations.

Note: Chinese Pharmacopoeia 1 is the quality standard and inspection standard of drugs formulated by our country. Most of the drugs are included in the Chinese Pharmacopoeia, and the quality standards of some drugs are not included in the Chinese Pharmacopoeia and exist as separate national standards. (must be approved by the Pharmacopoeia Committee). The company's drug registration standards are national trial standards starting with YBH.

1.3 Pharmaceutical excipients: Calcium carbonate can also be used as pharmaceutical excipients, added to medicines, and generally used as fillers.

Note: Pharmaceutical preparation regulations require the use of APIs.

2. Application of calcium carbonate in food industry:

The application of calcium carbonate in the food industry can be used as a food additive, a nutritional fortifier and as a base material in gum base (gum base or base material in gum base candy). my country has clear regulations on the scope and amount of additives used in the food industry.

2.1 Calcium carbonate is used as a food additive, and downstream customers must abide by GB2760 "Standards for the Use of Food Additives" (there will be different versions, which will be updated from time to time, and the latest version should be quoted when consulting). The relevant content of calcium carbonate is now excerpted as follows:

This product is used as leavening agent and flour treatment agent, and can be used in moderation according to production needs. (GB2760)

List of food categories with exceptions for this product to be used in moderation according to production needs (GB2760-A3)

Food classification number	Food name	Food classification number	Food name
01.01.01	Pasteurized milk	09.03	Prefabricated aquatic products (semi-finished products)
01.01.02	Sterilized milk	10.01	Fresh eggs
01.02.01	Fermented milk	10.03.01	Dehydrated egg products (eg protein powder, egg yolk powder, protein flakes)
01.03.01	Milk powder and cream powder	10.03.03	Frozen egg products (such as frozen eggs)
01.05.01	Cream	10.03.01	Dehydrated egg products (eg protein powder, egg yolk powder, protein flakes)
02.01	Essentially water-free fats and oils	10.03.03	Liquid and liquid eggs
02.02.01.01	Butter and condensed butter	11.01.01	White sugar and white sugar products (such as white granulated sugar, soft white sugar, rock sugar, cube sugar, etc.)
04.01.01	Fresh fruits	11.01.02	Other sugars and syrups (such as brown sugar, brown sugar, borneol, raw sugar, molasses, partially invert sugar, maple syrup, etc.)
04.02.01	Fresh vegetables	11.03.01	Honey
04.02.02.01	Frozen vegetables	12.01	Salt and salt substitutes
04.02.02.06	Fermented vegetable products	12.09	Spices
04.03.01	Fresh edible mushrooms and algae	13.01	Infant formula
04.03.02.01	Frozen edible mushrooms and algae	13.02	Infant Complementary Foods
06.01	Raw grain	13.03	Formula foods for special medical purposes (except for the varieties involved in 13.01)
06.02	Rice and its products	14.01.01	Drink natural mineral water
06.03.01	Wheat flour	14.01.02	Drinking pure water
06.03.02.01	Raw and wet noodle products (noodles, dumpling wrappers, wonton wrappers, shaomai wrappers)	14.01.03	Other drinking water
06.03.02.02	Raw and Dried Noodle Products (Noodles)	14.02.01	Fruit and vegetable juice (pulp)
08.01	Raw, fresh meat	14.02.02	Concentrated fruit and vegetable juice (pulp)
09.01	Fresh aquatic products	15.03.01	Wine
09.03	Prefabricated aquatic products (semi-finished products)	16.02	Tea, Coffee
10.01	Fresh eggs

This product is allowed to be added to wheat flour, and the maximum usage amount is 0.03g/kg. (GB2760)

.This product can be used in all kinds of food processing as a food industry processing aid, and the residue does not need to be limited (GB2760).

2.2 Calcium carbonate is used as a nutritional fortifier, and downstream customers must comply with GB14880 "Standards for the Use of Food Nutrition Fortifiers". The relevant content is now excerpted as follows:

As a nutritional fortifier, it is added according to the scope and dosage of the following table: (GB14880)

Food classification number	Food category (name)	Dosage (calculated as calcium)
01.01.03	Modified milk	250 mg/kg ~ 1000 mg/kg
01.03.02	Modified milk powder (except for children's milk powder)	3000 mg/kg ~ 7200 mg/kg
01.03.02	Modified milk powder (children's milk powder only)	3000 mg/kg ~ 6000 mg/kg
01.06	Cheese and Processed Cheese	2500 mg/kg ~ 10000 mg/kg
03.01	Ice cream	2400 mg/kg ~ 3000 mg/kg
04.04.01.07	Soy flour, soy milk powder	1600 mg/kg ~ 8000 mg/kg
06.02	Rice and its products	1600 mg/kg ~ 3200 mg/kg
06.03	Wheat flour and its products	1600 mg/kg ~ 3200 mg/kg
06.04	Multigrain powder and its products	1600 mg/kg ~ 3200 mg/kg
06.05.02.03	lotus root starch	2400 mg/kg ~ 3200 mg/kg
06.06	Ready-to-eat cereals, including rolled oats (flakes)	2000 mg/kg ~ 7000 mg/kg
07.01	Bread	1600 mg/kg ~ 3200 mg/kg
07.02.02	Western pastries	2670 mg/kg ~ 5330 mg/kg
07.03	Biscuit	2670 mg/kg ~ 5330 mg/kg
07.05	Other baked goods	3000mg/kg ~ 15000 mg/kg
08.03.05	Meat enemas	850 mg/kg ~ 1700 mg/kg
08.03.07.01	Meat floss	2500 mg/kg ~ 5000 mg/kg
08.03.07.02	Dried meat	1700 mg/kg ~ 2550 mg/kg
10.03.01	Dehydrated egg products	190 mg/kg ~ 650 mg/kg
12.03	Vinegar	6000 mg/kg ~ 8000 mg/kg
14.0	Beverages (except varieties involved in 14.01, 14.02 and 14.06)	160 mg/kg ~ 1350 mg/kg
14.02.03	Fruit and vegetable juice (meat) drinks (including fermented products, etc.)	1000 mg/kg ~ 1800 mg/kg
14.06	Solid beverages	2500 mg/kg ~ 10000 mg/kg
16.01	Jelly	390 mg/kg ~ 800 mg/kg

2.3 Calcium carbonate is used as a base material in gum base (gum base or base material in gum base candy), and the amount is used in an appropriate amount according to production needs. (GB29987 "Gum base and its ingredients").

3. Application of calcium carbonate particles:

The application of calcium carbonate particles has developed with the development of the health care product industry in recent years. To understand the application of calcium carbonate granules, first of all, let's understand the production process of tablets.

3.1 The production process of tablets: whether it is a drug tablet or a health product tablet, the processing technology is the same.

Calcium Carbonate D3 Tablets

It can be seen from the production process of the tablet that the granulation process of calcium carbonate granules belongs to the previous process of tablet production. The follow-up is only directly compressed into tablets (coated or uncoated) and then packaged.

3.2 Due to regulatory requirements, pharmaceutical tablet manufacturers are not allowed to subcontract part of their production processes to suppliers, but there are no special requirements for health care products regulations, so many health care product industries directly purchase calcium carbonate for cost savings or environmental protection requirements. After granulation, the production line is relatively simple, and some only need a tablet press to complete the entire production. Due to the strict management of those foreign-funded enterprises, the corresponding production costs are high, and the production costs are greatly reduced after reducing the process, which is also the reason why calcium carbonate particles are more popular at present.

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